Gene targeting
Oliver Smithies
He developed techniques for modifying genes in mice.
The problem
A question worth answering.
Introducing specific genetic changes was a major challenge.
What they did
He developed techniques for modifying genes in mice.
What changed
Gene targeting supports studies of disease mechanisms.
Where you meet their legacy
In the knowledge, systems and people who carry the work forward today.
Evidence and further reading
This story does not assign sole credit for a collective achievement.