Stem cells
Shinya Yamanaka
He showed mature cells could be reprogrammed into pluripotent cells.
The problem
A question worth answering.
Mature cells were thought to have fixed identities.
What they did
He showed mature cells could be reprogrammed into pluripotent cells.
What changed
Reprogramming created a major research tool.
Where you meet their legacy
In the knowledge, systems and people who carry the work forward today.
Evidence and further reading
This story does not assign sole credit for a collective achievement.